It depends.
Personally, I've always operated an 'if it is safe to do so' approach.
If the person has the time (i.e. they aren't more urgently needed elsewhere), support and reasonable expectation of safety, then sure, why not? The FRS will be provided with more information when they arrive (or may not need to attend at all), and if it is a false alarm, everyone can get back to work that much faster.
If however the receptionist is the only person in the building, or has no means of communication, or has any reason to believe that they would not be safe (there's smoke, they aren't familiar with the area, that floor is where you store the fireworks, whatever) then no way, no how. they get out, call 999 and explain the situation to the FRS.